Years following the events of The Shining (1980), a now-adult Dan Torrance must protect a young girl with similar powers from a cult known as The True Knot, who prey on children with powers to remain immortal.

On highways across America, a tribe of people called The True Knot travel in search of sustenance. They look harmless: mostly old, lots of polyester, and married to their RVs. But as Dan Torrance knows, and tween Abra Stone learns, The True Knot are quasi-immortal, living off the "steam" that children with the "shining" produce when they are slowly tortured to death.

Haunted by the inhabitants of the Overlook Hotel where he spent one horrific childhood year, Dan has been drifting for decades, desperate to shed his father's legacy of despair, alcoholism, and violence. Finally, he settles in a New Hampshire town, an AA community that sustains him, and a job at a nursing home where his remnant "shining" power provides the crucial final comfort to the dying. Aided by a prescient cat, he becomes "Doctor Sleep." Then Dan meets the evanescent Abra Stone, and her spectacular gift, the brightest shining ever seen, reignites Dan's own demons and summons him to a battle for Abra's soul and survival.