A recounting of the chaotic events that occurred at Dallas' Parkland Memorial Hospital on the day President John F. Kennedy was assassinated.

Recounting the chaotic events that occurred in Dallas, Texas, on November 22, 1963, "Parkland Memorial Hospital" weaves together the perspectives of several ordinary individuals suddenly thrust into extraordinary circumstances.

These include the young doctors and nurses, Dallas' chief of the Secret Service, an unwitting cameraman who captured what became the most watched and examined film in history, the FBI agents who nearly had the gunman within their grasp, the brother of Lee Harvey Oswald who was left to deal with his shattered family, and JFK's security team – all witnesses to both the president's death and Vice President Lyndon B. Johnson's rise to power over a nation whose innocence was forever altered.